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Lysergic acid diethylamide (LSD)

What is Lysergic acid diethylamide (LSD)?

Lysergic acid diethylamide (LSD) is a synthetic chemical substance which was originally found in a fungus that grows on the rye grain, called ergot. LSD is likely to be the most well known of the ‘classic’ psychedelic hallucinogens and is often labelled as one of the safer psychedelics for human consumption.

LSD is extremely powerful and only requires a tiny dose relative to most traditional psychedelics and other drugs. Doses are measured in the microgram (μg) range which can make it a very difficult and dangerous chemical to handle.

LSD is able to be absorbed through contact with the skin (transdermal) and there have been reports about people who have handled the pure chemical without the correct protection unemotionally ending up in a psychedelic trip.

The small dose range and difficulty handling the pure chemical gave way to alternative ways of storage and consumption. The most common form LSD will come is on blotting paper, also known as a tab. Blotting paper is a highly absorbent and is easily able to carry multiple doses of LSD in a single ¼-inch square piece. There are other forms of LSD available, either in pure crystal form (powerfully dangerous and not common), liquid form (often carrying many doses), blotter tabs, sugar cubes and microdots however the liquid LSD can easily be used to drop a standard dose onto just about anything that will absorb it.

Similar with other hallucinogens or psychedelics, the common effects that are associated with LSD include visual hallucinations, audible hallucinations and other sensory hallucinations (common known as tripping). LSD can have a range of effects on the thought patterns, emotions and general sense of self which can cause users to feel uncomfortable at times and potentially trigger a level of fear, anxiety and lead to a ‘bad trip’. The quality of the LSD experience depends largely on the dosage used, experience of the user, quality of the substance, mindset of the user prior to consumption and the setting in which the drug is being consumed.

LSD has a rather long duration compared to other classic psychedelics, with an average total experience time of 6-12 hours depending on dosage. Following consumption, the effects often take between 20-45 minutes to begin. A user may experience any combination of the following:

  • Increased heart-rate
  • Hallucinations
  • Euphoria
  • Faster breathing
  • Confusion
  • Uncontrollable laughter
  • Dilated pupils
  • New perspectives
  • Odd thought patterns
  • Decreased inhibitions
  • Increased creativity

The actual experience varies greatly between users and is considered to be very subjective.

How much LSD do people take?

According to, the oral dosage for LSD is as follows:

  • Threshold: 10 – 20 micrograms
  • Light: 20 – 75 micrograms
  • Common: 50 – 150 micrograms
  • Strong: 150 – 400 micrograms
  • Heavy: 400+ micrograms

The actual dosage found in common forms of LSD varies and is almost impossible to know exactly how much you will be consuming. This is largely due to the fact that LSD is transferred between many people after manufacture before it ends up on a blotter being sold on the street.

How long does an LSD trip last?

Similar to, the duration of effects for LSD are as follows:

  • Total Duration: 6 – 12 hours
  • Onset: 20 – 60 minutes
  • Come Up: 15 – 30 minutes
  • Plateau: 3 – 6 hours
  • Come Down: 3 – 5 hours
  • After Effects: 2 – 5 hours

Many users report an ‘afterglow’ following a positive experience after taking LSD. There is also potential for a user experiencing a difficult trip to have difficulty integrating the experience and returning to their usual daily frame of mind in the couple of days following the trip.

What are the safety risks of LSD use?

LSD can produce extremely powerful effects and has the ability to alter perceptions of life on earth for the user. This can be a confronting experience for those that are not prepared or well-researched in this chemical. It is very important to ensure a substance as mind-blowing as LSD is used in a controlled environment that the user is most comfortable in.

While there are no immediate health risks associated with LSD in terms of toxicity or physical danger, there is still the potential for a person under the influence to fall victim to poor decision making and put themselves in danger without considering the potential for harm.

The most common potential for health risk is the risk to the mental health of the user. This is believed to only become an issue if there are already underlying issues with mental health, whether they are already known or not. For example, if a person is already suffering from panic attacks or any other form of anxiety, this may be amplified due to the feeling of losing control when on a hallucinogenic drug such as LSD.

Microdosing LSD

Microdosing is the action of administering sub-perceptual doses of a substance which are not intended to produce noticeable effects to the user. A dose this low, although not capable of delivering standard psychotropic effects (dependent on the substance used), is still able to be used for the additional benefits associated with its use.

Microdosing LSD involves taking a dose considered to be a sub-threshold dose (often under 10μg). It is believed to provide nootropic effects that will benefit the user in their every day life without being committed to a full-blown psychedelic LSD trip for the usual length duration.

LSD microdosing is linked to increases in creativity, energy, appreciation for the simple things and a general feeling of euphoria felt throughout the day. There are many microdosing routines or recommended dosing protocols to maximise the experience, however each user is different an is encouraged to only follow something that feels right for them. It is important for the user to start small with a dose, and in an environment that is safe and suitable for testing out the correct dosing.

We have made a guide on Microdosing LSD, here.

Read through our other microdosing guides, here.

Feel through to read our articles about other substances, here.


5 favorite non-psychedelic substances for microdosing!

When you think of microdosing, the first two things that come to mind are usually LSD and Shrooms, the two most-used psychedelics for microdosing. Alternatively, many substances used for microdosing are Nootropics, or brain-enhancing drugs and food. For those who want the positive effects of MDing (increased focus, more energy, better relationship skills, etc) without using psychedelics, here are 5 substances that are commonly microdosed with positive effect.

  1. Modafinil
    Modafinil is commonly considered to be “the world’s first safe ‘smart drug’”. It is used as a stimulant, to clear your mind, unlock productivity, keep you focused, and even help cure depression. With a prescribed dose generally being between 100-400mg, microdoses can be larger than average, up to 50mg. One user found 25mg every other day was the perfect amount for positive effects, with no side effects. Though, upping his dose caused difficulty sleeping.
  2. Caffeine
    Overwhelming, caffeine seems to be the most microdosed non-psychedelic substance, though most who microdose caffeine aren’t usually aware that they are MDing. One study found that users who took. 0.3mg caffeine pills several times a day performed better on cognitive tests and slept fewer times during the day. Users themselves have said their energy tends to last longer throughout the day, with no crashing, if they sip caffeinated drinks over long periods, rather than drinking one or two cups in the morning.
  3. Xanax
    Xanax, when taken microdosed once or twice a day at 0.125mg has proven, with scientific study, to produce “small improvements in cognitive functions”. Anecdotally, users have found that using 0.125mg daily has helped them overcome depression and anxiety with none of the side effects caused at prescribed levels, such as memory problems or drowsiness. So science and microdosers themselves agree Xanax is a safe route for boosting brain power and boosting emotions.
  4. Prozac
    For those looking for relief from depression, panic disorder, or anxiety, science has said that low, regular doses of Prozac (Fluoxetine) can help calm your nerves and your depression. Users have also said their activity levels increased and decision-making is much easier. The therapeutic dose is 20-80mg but both scientists and users have found that between 5-12mg provides more benefits, with less side effects.
  5. Cocaine
    Results are mixed on microdosing cocaine. Some claim the results wear off so quickly you need another hit within 20 minutes, and you become easily addicted. Some take between 3-20mg in the morning and feel great the rest of the day. They experience great focus, more alertness, and uplifted moods. Many others commented that microdosing cocaine has been around for centuries by South Americans, who regularly chew large amounts of coca leaves, which results in small amounts of cocaine, daily. General consensus is that, if you easily get addicted, avoid cocaine. If you have great self control, MDing cocaine may be the way to go.

And there you have it, the five best non-psychedelic substances for microdosing. With most of these substances you’ll still get most of the same effects as microdosing psychedelics, but with some (arguably) safer options.


Benefits of microdosing psychedelics!

Benefits Of Microdosing Psychedelics

Before we talk about the benefits, risks and different aspects of microdosing, we first need to understand what actually this is. Microdosing is a process or practice of taking small amount of psychedelic drugs in order to achieve certain positive results and effects.

The idea of microdosing (for example: microdosing LSD) is derived from the pharmaceutical industry. The idea is to use or consume the minimum amount of drugs or medicines in order to get required results without any negative effects. A microdose is actually the one tenth or half of the normal dose. The most common microdose include microdosing mushrooms and microdosing LSD.

Benefits of Microdosing Psychedelic

When it comes to the benefits of microdosing mushroom or microdosing LSD, there are no particular studies or research that show the data regarding its calculated benefits. However, a lot of other reports are available that have highlighted the proposed benefits and we will include most important of these.

  1. Anxiety

If you are suffering from anxiety, whether it is academic, general or social, the microdosing will help you get rid of it. In start you will feel a slight reduction in anxiety and the regular use will be even more effective in this regard.

  1. Athletic Performance

The reports available on the benefits of microdosing show these are also helpful for athletic performance. In case you want to boost your energy or stamina, the microdose will of great help.

  1. Creativity

Here comes another amazing benefit of microdosing and that is they help people improve their creativity. In other words, they are helpful for cognitive enhancement and make you a more creative person.

  1. Depression

Just like anxiety, the reports have also listed the benefits of microdosing mushrooms for depression. This is a serious issue for millions of people but the microdose have saved a lot of people by helping them against depression.

  1. Empathy and Healthy Choices

This might be interesting to find out that microdosing LSD is helpful if you want to be a more empathic person and feel for others. This makes you show great care and consideration for other people around you. Moreover, a person also become pickier in his health and prefers healthy activities, foods, exercise and diets.

  1. Learning and Job Performance

As stated earlier, these drugs are good to enhance creativity and improve productivity. If you are someone who is a regular leaner and wants to be more attentive to the details, these will help you become a better learner. This include computer knowledge, programming, languages, complex situations or puzzles. Similarly, a person with microdosing also notices a great improvement in job and what they do. Even, you become a more satisfied person who enjoys his job.

  1. Mood Elevation and Problem Solving

When the creativity is increased and productivity improves, a person become more talented or sharp in solving problems around. Whether it be any kind of problem, you will feel you have become more responsive towards issues. Furthermore, there is also a noticeable change in the mood and it keeps improving with passage of time.